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. 2012 Jan 17;7(1):e30481. doi: 10.1371/journal.pone.0030481

Figure 3. Acute stress modulates BDNF profile differentially in CA3 and BLA.

Figure 3

Data are presented as mean ± SEM. A Experimental design of acute stress (AIS+1d) and recovery for 10 days from acute stress (AIS+10d). B BDNF expression in area CA3 in response to acute stress. Acute stress does not change the BDNF levels in CA3 (Control, n = 9; AIS+1d, n = 9; AIS+10d, n = 6, F(2,21) = 2.11, p>0.05). C Acute stress up regulates BDNF expression in BLA and this up regulation persists even after recovery (Control, n = 6; AIS+1d, n = 5; AIS+10d, n = 6, F(2,14) = 4.82, p<0.05). BDNF expression profile was normalized to respective control levels and evaluated by Fisher's post-hoc. D Effect of acute stress and recovery from acute stress on serum corticosterone levels (Control, n = 11; AIS+1d, n = 5; AIS+10d, n = 6, Kruskal-Wallis ANOVA, χ2 (2) = 10.01, p<0.05, Mann-Whitney post-hoc, p<0.05). Significant differences *, p<0.05.