Table 3. Susceptibility of L. tropica clinical isolates to antileishmanial drugs.
| Strains | EC50 a | |||||
| AmphotericinB (µg/ml) | Paromomycin (µg/ml) | Miltefosine (µg/ml) | Pentostam (µg/ml) | Malarone (µg/ml) | Fluconazole(µg/ml) | |
| 175 | 0.51±0.08 | 19.0±8.1 | 0.19±0.07 | 300±32 | >8 | >275 |
| 017102 | 0.59±0.29 | 7.4±1.7 | 0.11±0.004 | 188±39 | 6.6±0.1 | >275 |
| 431462 | 0.32±0.18 | 3.2±0.9 | 0.09±0.004 | 142±4 | 3.6±0.6 | >275 |
| 072218 | 0.51±0.07 | 9.8±1.8 | 0.15±0.07 | 142±12 | 4.4±1.1 | >275 |
| 18693 | 0.72±0.33 | 5.8±4.8 | 0.65±0.33 | ND | >8 | >275 |
a
Determined as amastigotes in THP-1 cells.