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. 2011 Feb 24;34(1):247–267. doi: 10.1007/s11357-011-9217-5

Table 1.

Interesting questions and hot topics

How do nationality-related features, such as diet, environment and life style, impact the ageing of the intestinal microbial community?
How does the individual physiological health status determine the threshold of ageing of the intestinal microbiota?
Can we find specific microbial metabolites biomarkers of the ageing process?
How is possible to modulate the ageing process of the intestinal microbiota?
Which is the right intervention time for the modulation of the ageing process of the human intestinal microbiota?