Table 2.
Association between serum inflammatory markers and thyroid function parameters
| Change per standard deviation increase | ||
|---|---|---|
| All subjects | Restricted to CRP levels ≤ 10 (mg/dL) | |
| Ln C-Reactive protein | ||
| ln thyrotropin (mU/L) | 0.02 (0.03) | 0.04 (0.05) |
| p value | 0.57 | 0.32 |
| Free thyroxine (pmol/L) | 0.07 (0.10) | −0.09 (0.13) |
| p value | 0.47 | 0.52 |
| Free triiodothyronine (pmol/L) | −0.07 (0.02) | −0.05 (0.03) |
| p value | 0.001 | 0.09 |
| Ln unstimulated IL-6 | ||
| ln thyrotropin (mU/L) | 0.02 (0.03) | 0.03 (0.04) |
| p value | 0.57 | 0.40 |
| Free thyroxine (pmol/L) | 0.05 (0.10) | 0.01 (0.11) |
| p value | 0.59 | 0.92 |
| Free triiodothyronine (pmol/L) | −0.05 (0.02) | −0.03 (0.02) |
| p value | 0.020 | 0.25 |
Data are given as mean change (with standard error of the mean) in serum thyroid parameter per standard deviation increase in ln C-Reactive protein and Ln unstimulated IL-6
Analyses were adjusted for sex
LPS lipopolysaccharide