Table 4.
Clinical end point* | Predictor variable | Regression coefficient | 95% Confidence interval | p Value |
---|---|---|---|---|
FEV1 | F508del homozygotes | -0,511 | -1,016 to -0,048 | 0,034 |
Pseudomonas + | -0,376 | -0,741 to -0,010 | 0,044 | |
| ||||
FVC | F508 del homozygotes | -0,551 | -1,026 to -0,072 | 0,027 |
F508 del heterozygotes | -0,584 | -0,943 to−0,220 | 0,003 | |
| ||||
FEV1/FVC | Smoking mother during Pregnancy (Cig/week) | -0,385 | -0,416 to -0,007 | 0,043 |
Expressed as percentage predicted. The following predictor variables were included: cotinine concentration, mother smoking during pregnancy (dicotoumus and cig/week), F508del groups, pseudomonas colonization, smoking father at home, father’s packet per years. To obtain predictor variables the comparisons of all variables were made using the unpaired Student’s t test, ANOVA test and Spearman’s rho correlation.