Table 2.
S. pneumoniae CFU in cultures from both nares as a function of time post-instillation
Animal/Weeks PI | S. pneumoniae CFU*** | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | |
IG74 | >100 | >150 | - | - | - | - | - | - | - | - | - | - | >100 | >500 |
IH49 | 600 | TMTC | - | >375 | 3 | 250 | >120 | 2 | - | - | - | 2 | - | - |
IH65 | 2 | >100 | 100 | <10 | - | <10 | - | - | - | - | - | - | - | >100 |
IJ55 | 42 | >450 | 200 | >220 | >20 | - | 1 | - | ** | - | - | - | - | - |
IJ92* | >250 | TMTC | TMTC | TMTC | >400 | 1 | >50 | - | 9 | - | - | - | - | - |
IJ99* | >400 | TMTC | TMTC | >700 | TMTC | 250 | >5 | - | 10 | - | >400 | >100 | - | - |
IM44* | >200 | TMTC | TMTC | >400 | >200 | - | >100 | - | >200 | - | - | - | - | - |
IG99* | >250 | >350 | TMTC | >300 | TMTC | >170 | >200 | 25 | >225 | 12 | >260 | 150 | 28 | - |
animals that were splenectomized (at 6 weeks post-instillation, shaded column).
no swab was taken from this animal at this time.
CFU from both nares were counted and added for each of the time points.