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. 2011 Aug 29;23(1):70–82. doi: 10.1089/hum.2011.016

Table 1.

Viral Yield and Infectivity Ratio of Wild-Type and Recombinant Viruses

Virus PP/mla(× 1012) PP/PFUa
Ad[WT] 2.9±0.7 50±31
Ad[ZH/1] 1.8±0.8 140±23
Ad[ZH/2] 2.1±0.2 805±162
Ad[ZH/3] 1.6±1.4 620±202

Ad[ZH/1], Her2/neu-targeted and CAR-detargeted virus; Ad[ZH/2], virus with ablation of CAR binding and mutation of RKSK; Ad[ZH/3], virus with mutation of all three binding structures; PFU, plaque-forming unit; PP, physical particles; WT, wild type.

a

Measurements from two or three different CsCℓ purifications of 10 infected 175-cm2 flasks, displayed as the average±SD.