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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Int J STD AIDS. 2011 Jun;22(6):310–314. doi: 10.1258/ijsa.2009.009363

Table 2.

HIV-1 viral load as measured by ultrasensitive heat-denatured HIV-1 p24 antigen assay (Up24) (log10 fg/ml) compared to reverse transcriptase-polymerase chain reaction analysis (RT-PCR) (copies/ml).

HIV-1 viral load by RT-
PCR (copies/ml)
< 400 400–
50,000
50,000–
100,000
100,000–
250,000
250,000–
500,000
>500,000
Number of samples tested 114 62 37 72 50 59
Number detected by Up24 38 28 23 49 40 53
Median Up24 (log10 fg/ml)
(Interquartile range)
1.9
(1.9–2.7)
1.9
(1.9–3.2)
3.4
(1.9–4.2)
3.6
(1.9–4.2)
3.9
(3.2–4.4)
4.1
(3.5–4.7)
Sensitivity of Up24*
(95% CI)
33%
(25–42%)
45%
(33–58%)
62%
(47–78%)
68%
(57–79%)
80%
(69–91%)
90%
(82–98%)
*

Number of samples detected by Up24/number of samples tested.

Χ2, test for trend, p-value < 0.0001.