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. 2011 Dec;179(6):3056–3065. doi: 10.1016/j.ajpath.2011.08.042

Table 1.

Pathway Analysis for Changes in Gene Expression in Ogg1−/− Mice 24 Hours after UVB Exposure

Pathway name Total genes (no.) Changed expression (no.) P value
Increased Expression
 Inflammatory response 39 7 0.000054
 Complement/coagulation 56 7 0.00042
 Striated muscle contraction 41 5 0.0032
 Complement activation (classical pathway) 13 3 0.0049
Decreased Expression
 Hypertrophy model 19 3 0.0015
 GPCR (class A, rhodopsin-like) 187 7 0.0035
 Id signaling pathway 48 3 0.016
 Small ligand GPCRs 19 2 0.020

GPCR, G protein-coupled receptor.

Top four pathways involving significantly increased or decreased gene expression, as extracted from microarray data.