Table 4. Estimated global burden of chronic pulmonary aspergillosis (CPA) after pulmonary tuberculosis (TB), by World Health Organization (WHO) region, for different rates of annual attrition (10–25%) and CPA frequency estimatesa.
CPA frequency |
Global |
Europe |
Africa |
Eastern Mediterranean |
Americas |
Western Pacific |
South-East Asia |
|||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TB cavity | No TB cavity | 10% | 15% | 25% | 10% | 15% | 25% | 10% | 15% | 25% | 10% | 15% | 25% | 10% | 15% | 25% | 10% | 15% | 25% | 10% | 15% | 25% |
30% | 4% | 2 088 604 | 1 786 412 | 1 296 646 | 68 111 | 58 256 | 42 284 | 551 639 | 471 825 | 342 469 | 115 395 | 98 699 | 71 639 | 70 584 | 60 371 | 43 820 | 469 154 | 401 274 | 291 260 | 813 721 | 695 987 | 505 174 |
22% | 4% | 1 713 570 | 1 465 640 | 1 063 817 | 58 927 | 56 401 | 36 583 | 451 754 | 386 392 | 280 458 | 94 500 | 80 828 | 58 668 | 57 803 | 49 440 | 35 885 | 384 204 | 328 615 | 238 522 | 666 381 | 569 965 | 413 702 |
22% | 2% | 1 372 457 | 1 173 881 | 852 048 | 42 091 | 36 001 | 26 131 | 363 219 | 310 667 | 225 494 | 75 980 | 64 987 | 47 170 | 46 475 | 39 751 | 28 852 | 308 908 | 264 213 | 191 776 | 535 783 | 458 263 | 332 625 |
22% | 1% | 1 201 900 | 1 028 002 | 746 163 | 33 673 | 28 801 | 20 905 | 318 952 | 272 804 | 198 012 | 66 720 | 57 067 | 41 421 | 40 811 | 34 906 | 25 336 | 271 260 | 232 012 | 168 403 | 470 485 | 402 412 | 292 086 |
10% | 1% | 639 349 | 546 844 | 396 920 | 19 898 | 17 019 | 12 353 | 169 124 | 144 654 | 104 995 | 35 378 | 30 260 | 21 964 | 21 640 | 18 509 | 13 434 | 143 835 | 123 024 | 89 296 | 249 474 | 213 379 | 154 878 |
a Estimated frequency was 10–30% in patients with cavities and 1–4% in patients without cavities after completion of anti-tuberculous therapy.