Table 2. Allele and haplotype frequency data.
| NRY | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R1a1 | I | J2 | R1 xR1a1 | F xI/J2/R1 | E | n | ||||||||||
| SW | 0.013 | 0.150 | 0.025 | 0.750 | 0.038 | 0.025 | 80 | |||||||||
| CN | 0.053 | 0.140 | 0.018 | 0.684 | 0.105 | 0.000 | 57 | |||||||||
| E | 0.035 | 0.161 | 0.023 | 0.598 | 0.138 | 0.046 | 87 | |||||||||
| N | 0.022 | 0.202 | 0.033 | 0.656 | 0.071 | 0.016 | 183 | |||||||||
| OR | 0.342 | 0.079 | 0.000 | 0.579 | 0.000 | 0.000 | 38 | |||||||||
| HLA-A | HLA-B | HLA-C | ||||||||||||||
| |
01 |
02 |
03 |
11 |
2n |
07 |
08 |
15 |
35 |
44 |
2n |
03 |
05 |
06 |
07 |
2n |
| SW | 0.169 | 0.307 | 0.156 | 0.055 | 326 | 0.151 | 0.170 | 0.077 | 0.071 | 0.106 | 311 | 0.123 | 0.141 | 0.083 | 0.368 | 326 |
| CN | 0.191 | 0.270 | 0.157 | 0.071 | 267 | 0.139 | 0.147 | 0.053 | 0.090 | 0.109 | 266 | 0.167 | 0.104 | 0.089 | 0.333 | 270 |
| E | 0.172 | 0.304 | 0.175 | 0.052 | 326 | 0.134 | 0.130 | 0.103 | 0.103 | 0.090 | 322 | 0.175 | 0.089 | 0.092 | 0.316 | 326 |
| N | 0.177 | 0.271 | 0.151 | 0.076 | 661 | 0.186 | 0.105 | 0.060 | 0.081 | 0.124 | 651 | 0.131 | 0.122 | 0.087 | 0.366 | 666 |
| OR | 0.183 | 0.291 | 0.091 | 0.080 | 175 | 0.222 | 0.090 | 0.084 | 0.030 | 0.204 | 167 | 0.171 | 0.114 | 0.091 | 0.381 | 176 |
| HLA-DRB1 | HLA-DQB1 | |||||||||||||||
| |
01 |
03 |
04 |
07 |
11 |
13 |
15 |
2n |
02 |
03 |
05 |
06 |
2n |
|
|
|
| SW | 0.106 | 0.156 | 0.240 | 0.100 | 0.065 | 0.109 | 0.122 | 321 | 0.225 | 0.338 | 0.184 | 0.225 | 320 | |||
| CN | 0.105 | 0.165 | 0.173 | 0.102 | 0.094 | 0.109 | 0.132 | 266 | 0.229 | 0.342 | 0.150 | 0.259 | 266 | |||
| E | 0.079 | 0.142 | 0.195 | 0.145 | 0.085 | 0.101 | 0.123 | 318 | 0.280 | 0.341 | 0.137 | 0.213 | 314 | |||
| N | 0.116 | 0.144 | 0.177 | 0.147 | 0.055 | 0.090 | 0.164 | 654 | 0.262 | 0.308 | 0.150 | 0.253 | 652 | |||
| OR | 0.061 | 0.141 | 0.160 | 0.184 | 0.043 | 0.086 | 0.209 | 163 | 0.267 | 0.320 | 0.111 | 0.273 | 172 | |||
| HLA-A, -B and -DRB1 haplotypes | ||||||||||||||||
| |
01-08-03 |
03-07-15 |
02-44-04 |
02-07-15 |
02-15-04 |
29-44-07 |
2n |
|
|
|
|
|
|
|
|
|
| SW | 0.076 | 0.023 | 0.030 | 0.020 | 0.030 | 0.003 | 304 | |||||||||
| CN | 0.088 | 0.023 | 0.012 | 0.012 | 0.008 | 0.008 | 260 | |||||||||
| E | 0.077 | 0.026 | 0.016 | 0.026 | 0.019 | 0.016 | 310 | |||||||||
| N | 0.062 | 0.019 | 0.021 | 0.015 | 0.011 | 0.011 | 623 | |||||||||
| OR | 0.051 | 0.013 | 0.044 | 0.051 | 0.013 | 0.044 | 158 | |||||||||
| MC1R (rs1805007) | MC1R (rs1805008) | ABO (rs7853989) | ||||||||||||||
| |
C |
2n |
C |
2n |
C |
2n |
|
|
|
|
|
|
|
|
|
|
| SW | 0.906 | 340 | 0.945 | 328 | 0.929 | 328 | ||||||||||
| CN | 0.924 | 264 | 0.909 | 264 | 0.893 | 270 | ||||||||||
| E | 0.908 | 326 | 0.932 | 310 | 0.920 | 326 | ||||||||||
| N | 0.910 | 652 | 0.934 | 664 | 0.914 | 660 | ||||||||||
| OR | 0.887 | 194 | 0.906 | 192 | 0.828 | 192 | ||||||||||
The NRY haplogroups are those that are the most common in Europe, while the HLA alleles (low, allele group, resolution) are those that have a frequency of >7.5% in at least one region. The estimated frequencies of the six most common HLA-A, -B -and DRB1 haplotypes are also shown. Only the major allele frequencies are presented for the MC1R and ABO SNPs. Populations are grouped into regions as defined in the main text. The regions are: SW (Cornwall, Devon and Pembrokeshire), CN (Oxfordshire and the Forest of Dean), E (Sussex, Kent, Norfolk and Lincolnshire), N (Cumbria, Yorkshire and the North East) and OR (Orkney).