Figure 1.
Representative dot plots for lymphocytes in spleen (A) and bone marrow (B) of mice bearing the anti-α3(IV)NC1 collagen IgMa,kappa antibody transgenes (Tg+). Log fluorescence data for stained unstimulated cells gated on lymphocytes on the basis of forward and side scatter (all plots), with further gating on B220+ populations where indicated. B220 is a B cell marker. IgM-a allotype identifies the transgene heavy chain, IgM-b allotype identifies endogenous heavy chains.