Schematic depicting the cross-sectional view of PF-108 conformation in/on PLGA microfiber surface. (A) Change in conformation of ethylene oxide units of PF-108 from mushroom-shaped to brush-shaped conformation with increase in surface density of PF-108 on PLGA microfiber surface. (B) Primary and secondary protein adsorption behavior on mushroom-shaped and brush-shaped ethylene oxide units.
Abbreviations: PF, Pluronic® F; PLGA, polylactide-co-glycolide; EO, ethylene oxide; PO, propylene oxide.