Table 3.

Correlations and Associations between Cytokines and Clinical and Histopathologic Parameters and between Cytokines and Survival

	Cytokines														Test Applied
	IL-6	IL-10	bFGF	GM-CSF	IP-10	MCP-1	MIP-1α	RANTES	VEGF	MCP-3	MIF	TRAIL	ICAM-1	VCAM-1
Ciliary body ingrowth	0.04	0.60	0.13	0.05	0.81	0.26	0.08	0.05	0.21	0.30	0.04	0.22	0.16	0.11	t-Test
Largest basal diameter	0.13	0.39	0.31	0.06	0.44	0.43	0.32	0.03	0.91	0.91	0.40	0.84	0.78	0.86	Spearman's correlation
Prominence	0.67	0.63	0.38	0.55	0.94	0.43	0.74	0.81	0.02	0.58	0.26	0.73	0.74	0.83	Spearman's correlation
Tumor size pTNM (7th edition)	0.71	0.40	0.10	0.98	0.48	0.54	0.88	0.50	0.77	0.99	0.31	0.92	0.99	0.51	ANOVA
Presence of epithelioid cell type	0.77	0.47	0.89	0.28	0.47	0.91	0.69	0.96	0.80	0.02	0.86	0.22	0.36	0.96	t-Test
Microvascular density	0.21	0.69	0.42	0.82	0.42	0.33	0.15	0.08	0.81	0.08	0.79	0.39	0.33	0.70	ANOVA
Presence of monosomy 3	0.48	0.40	0.63	0.52	0.46	0.50	0.08	0.31	0.77	0.13	0.94	0.22	0.11	0.30	t-Test
HLA class I with HC10 staining	0.72	0.40	0.13	0.97	0.08	0.93	0.19	0.64	0.56	0.59	0.20	0.18	0.15	0.59	Spearman's correlation
HLA class I with HCA2 staining	0.91	0.39	0.74	0.78	0.56	0.39	0.85	0.60	0.15	1.00	0.49	0.13	0.12	0.08	Spearman's correlation
HLA Class II with HLA-DR staining	0.26	0.97	0.23	0.03	0.80	0.55	0.46	0.11	0.75	0.03	0.95	0.01	0.27	0.78	Spearman's correlation
Survival analysis	0.21	0.92	0.47	0.99	0.16	0.30	0.40	0.06	0.40	0.71	0.31	0.65	0.39	0.94	Cox regression

P-values shown in bold indicate a significant correlation.