Table 2.

Gene data expressed relative to respective Sham values

Category	Transcript	Hypothalamus					Brainstem
		WT + Sham	MI + VEH	MI + ETN	KO + Sham	KO + MI	WT + Sham	MI + VEH	MI + ETN	KO + Sham	KO + MI
n		8	10	8	8	10	8	10	8	8	10
Cytokines	TNF	1.04 ± 0.21	2.38 ± 0.09*	0.40 ± 0.34#	1.07 ± 0.23	0.88 ± 0.06	0.61 ± 0.09	2.01 ± 0.17	0.81 ± 0.85*	1.02 ± 0.12	1.15 ± 0.09
	IL-1β	1.26 ± 0.30	3.73 ± 0.06*	1.30 ± 0.45#	1.04 ± 0.17	1.52 ± 0.43	1.06 ± 0.13	2.81 ± 0.36*	1.96 ± 1.00	1.06 ± 0.22	1.39 ± 0.29*
	IL-6	1.12 ± 0.28	1.64 ± 0.11	1.08 ± 0.38	1.06 ± 0.19	0.96 ± 0.08	1.11 ± 0.20	1.38 ± 0.14	1.02 ± 0.31	1.04 ± 0.11	1.11 ± 0.18
	IL-10	1.08 ± 0.17	1.11 ± 0.08	4.31 ± 1.96*,#	1.06 ± 0.24	3.13 ± 0.66*	1.05 ± 0.11	0.53 ± 0.03	2.21 ± 1.71*	1.07 ± 0.19	1.01 ± 0.13
Nitric oxide synthases	nNOS	1.19 ± 0.41	0.59 ± 0.09*	1.27 ± 0.22#	1.40 ± 0.47	1.84 ± 0.11	1.14 ± 0.32	0.69 ± 0.09*	1.26 ± 0.42#	1.03 ± 0.14	1.66 ± 0.36
	eNOS	1.19 ± 0.40	0.90 ± 0.10	1.20 ± 0.05*	1.04 ± 0.16	1.94 ± 0.25*	1.15 ± 0.34	1.07 ± 0.07	1.26 ± 1.13	1.06 ± 0.21	1.76 ± 0.20*
	iNOS	0.92 ± 0.11	2.57 ± 0.12*	0.98 ± 0.06#	1.08 ± 0.25	0.75 ± 0.05	0.58 ± 0.03	0.90 ± 0.19	1.24 ± 0.16*	1.04 ± 0.17	0.63 ± 0.06*
Nox homologs	Nox2	1.12 ± 0.25	3.08 ± 0.38*	1.84 ± 0.33#	1.03 ± 0.13	1.21 ± 0.24	1.22 ± 0.46	1.96 ± 0.25	1.88 ± 0.23	1.01 ± 0.08	0.80 ± 0.17
	Nox4	1.17 ± 0.39	1.58 ± 0.15	0.99 ± 0.08	1.01 ± 0.08	0.84 ± 0.12	1.38 ± 0.66	1.28 ± 0.11	1.03 ± 0.07	1.01 ± 0.07	0.78 ± 0.04
AngII receptors	AT1R	1.07 ± 0.24	1.96 ± 0.19*	0.92 ± 0.12#	1.03 ± 0.16	0.64 ± 0.09	1.04 ± 0.31	1.79 ± 0.0*	1.04 ± 0.16#	1.04 ± 0.18	0.76 ± 0.03
	AT2R	1.18 ± 0.38	0.86 ± 0.09	1.56 ± 0.04	1.03 ± 0.14	1.97 ± 0.26*	1.13 ± 0.35	0.81 ± 0.09	1.28 ± 1.17	1.29 ± 0.44	1.42 ± 0.07

Values expressed are means ± SEM of relative gene expression (2^−ΔΔCt) to respective sham group with sham values arbitrarily set at 1.

^*p < 0.05 as compared to respective sham group,

^#p < 0.05 as compared to MI + VEH group