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. 2011 Dec 16;11:341. doi: 10.1186/1472-6963-11-341

Table 2.

Tuberculosis patient and treatment characteristics associated with taking less than 90% of prescribed doses of anti-TB treatment

< 90% drug adherence Univariate Adjusted
N n % OR 95% CI p-value OR 95% CI

Province 0.02

Anhui 105 11 10.5% 1.00

Ningxia 104 0 0% -- --

Jiangxi 105 9 8.6% 0.80 0.32-2.02

Guizhou 105 22 21.0% 2.27 1.04-4.95

Ganshu 105 7 6.7% 0.61 0.23-1.64

Education level 0.04

No formal education 142 7 4.9% 1.00

At least primary school 382 42 11.0% 2.38 1.04-5.43

TB patient category 0.20

New 476 42 8.8% 1.00

Retreatment 48 7 14.6% 1.76 0.75-4.18

Adverse effects during treatment < 0.01

Yes 312 41 13.1% 1.00 1.00

No 212 8 3.8% 0.26 0.12-0.57 0.30 0.17-0.53

DOT during the intensive phase < 0.01

no DOT 241 33 13.7% 1.00 1.00

DOT by village doctors 153 5 3.3% 0.21 0.08-0.56 0.28 0.09-0.82

DOT by volunteers 130 11 8.5% 0.58 0.28-1.20 0.44 0.19-1.03

DOT during continuation phase 0.02

no DOT 253 31 12.3% 1.00

DOT by village doctors 136 4 2.9% 0.22 0.08-0.63

DOT by volunteers 135 14 10.4% 0.83 0.42-1.62

Supervision visits by (village) doctor during treatment < 0.001

Yes 462 35 7.6% 1.00

No 62 14 22.6% 3.56 1.79-7.08

Time DOT observer spends with the patient during observation of treatment 0.003

DOT at home, ≤10 minutes 181 10 5.5% 1.00 1.00

DOT at home, > 10 minutes 198 15 7.6% 1.40 0.61-3.20 2.10 0.82-5.42

DOT outside home or no DOT 145 24 16.6% 3.39 1.57-7.35 3.49 1.42-8.62