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. 2012 Jan 3;12:2. doi: 10.1186/1471-2229-12-2

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Copyright ©2011 Rapala-Kozik et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Schematic representation of thiamine biosynthesis in plants (A) and subcellular localization of the major thiamine diphosphate-incorporating enzymes (B). The Arabidopsis genes encoding the enzymes which catalyze the biosynthetic reactions shown are specified. AIR, 5-aminoimidazole ribonucleotide; HET-P, 4-methyl-5-(2-hydroxyethyl)thiazole phosphate; HMP-P/HMP-PP, 4-amino-2-methyl-5-hydroxymethylpyrimidine monophosphate/diphosphate; TA, thiamine; TMP, thiamine monophosphate; TDP, thiamine diphosphate; PDC, pyruvate decarboxylase; PDH, pyruvate dehydrogenase; KGDH, α-ketoglutarate dehydrogenase; BKDH, branched-chain α-ketoacid dehydrogenase; TK, transketolase; DXPS, 1-deoxy-D-xylulose-5-phosphate synthase.