Table 2. Stratification for the test of heterogeneity on IL-8 -251 AA vs TA based on a codominant model.
Q-test | OR(95%CI) | P value | |||
chi-squared | d.f. | p | |||
Overall | 35.96 | 17 | 0.005 | 1.17(0.98–1.40) | 0.092 |
Large sample | 23.18 | 9 | 0.006 | 1.12 (0.90–1.40) | 0.305 |
Small-and-moderate sample | 11.75 | 7 | 0.109 | 1.25 (0.98–1.59) | 0.067 |
High quality | 17.88 | 10 | 0.057 | 1.25 (1.03–1.51) | 0.023 |
Low-and-moderate quality | 14.28 | 6 | 0.027 | 1.03 (0.71–1.49) | 0.892 |
Publication before or in 2005 | 17.20 | 5 | 0.004 | 1.23(0.82–1.85) | 0.326 |
Publication after 2005 | 18.40 | 11 | 0.073 | 1.13 (0.93–1.37) | 0.222 |
Caucasians | 0.98 | 3 | 0.806 | 0.93 (0.76–1.13)* | 0.453# |
Asians | 27.54 | 12 | 0.006 | 1.31 (1.04–1.66) | 0.024 |
Non-cardia type | 4.56 | 7 | 0.714 | 0.85 (0.70–1.04)* | 0.122# |
Cardia type | 4.77 | 4 | 0.311 | 1.22 (0.97–1.55)* | 0.092# |
Intestinal type | 4.96 | 6 | 0.549 | 1.08 (0.83–1.40)* | 0.583# |
Diffuse type | 6.42 | 3 | 0.093 | 0.89 (0.52–1.53) | 0.672 |
Hp positive | 14.11 | 3 | 0.003 | 1.22 (0.62–2.43) | 0.564 |
Hp negative | 2.43 | 2 | 0.297 | 0.88 (0.57–1.38) | 0.589 |
PCR-RFLP genotyping | 12.46 | 6 | 0.052 | 1.07 (0.82–1.41) | 0.607 |
Other genotyping | 23.23 | 10 | 0.010 | 1.25 (0.97–1.61) | 0.084 |
*: M-H ORs (95% CI), otherwise D+L ORs (95% CI).
: P values of M-H estimates, otherwise P values of D+L estimates.