Table 1. In vitro susceptibility against representative strains of clinically relevant bacterial pathogens for merochlorin A.
Susceptibility Test MIC (mg/L) | ||
Broth Microdilution | Agar Dilution | |
Streptococcus pneumoniae (D39) | 2 | ND |
Streptococcus pyogenes (5448, NZ131) | 4 | ND |
Streptococcus agalactiae (COH1) | 4 | ND |
Bacillus cereus | 2 | ND |
Staphylococcus epidermidis (ATCC12228) | 4 | ND |
MRSA (ATCC33591) | 2 | 1 |
MSSA (ATCC29213) | 4 | 2 |
Vancomycin-resistant Enterococcus faecium | 2 | 1 |
Vancomycin-resistant Enterococcus faecalis | 1 | 1 |
Clostridium dificile ATCC 700057 | 0.3 | ND |
Clostridium dificile (BI) | 0.15 | ND |
Pseudomonas aeruginosa | >64 | >64 |
Escherichia coli ATCC25922 | >64 | >64 |
Enterobacter cloacae | >64 | >64 |
Acinetobacter baumanii | >64 | >64 |
Klebsiella pnemoniae | >64 | >64 |