Table 1. Quantitative analysis of OTUB1 immunoreactivity in glomerulonephritides.

groups	n	mean density(IOD/AOI)
Normal	8	0.002096±0.00034
MCD	8	0.004506±0.002153
MGN	7	0.004028±0.002089
IgAN	10	0.03412±0.003823**
APGN	12	0.065412±0.020209**
LN	10	0.088363±0.034724**

Immune staining of OTUB1 was quantitatively assessed on the mean density (ratio of integrated optical density (IOD) to area of interest (AOI) per glomerulus in normal kidney tissue and some nephropathy tissues. The expression of OTUB1 was statistically significantly higher in IgA nephropathy, acute diffuse proliferative glomerulonephritides and lupus nephritis than that in normal kidney tissue (**P<0.01).