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. 2012 Jan 18;7(1):e29812. doi: 10.1371/journal.pone.0029812

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Della Santina et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: averaged ERG responses of increasing light intensity in the HCN^+/+ (gray, n = 18), HCN1^−/− (red n = 18) and HCN2^−/− (blue, n = 10). Dim, intermediate and bright flash intensities are shown in the left, middle and right panel, respectively. B–C: collected data of the b-wave peak amplitude as a function of the flash intensity in HCN^+/+, HCN1^−/− and HCN2^−/−, relative amplitudes were normalized at their maximum value. The intensity of the flash is expressed as a number of photoisomerizations per rod (Φ) per flash. The dotted ovals in B indicate the dim, intermediate and bright flash responses illustrated in A.