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. 2012 Jan 18;7(1):e30033. doi: 10.1371/journal.pone.0030033

Figure 3. WASp and its phosphorylation are required for the persistence of chemotactic protrusion.

Figure 3

Quantification of the protrusive responses of shControl, shWASp and Y291F cells in response to CSF-1 supplying micropipette from time lapse images are shown. (A) Onset of the protrusion (time after CSF-1 stimulation), (B) duration of the protrusion, (C) maximum length of the protrusion and (D) protrusion rate (maximum length/time it takes the protrusion to reach maximum length) in response to CSF-1 were determined. The data represent the mean of at least 30 cells from seven separate videos. Error bars represent SEM. * p<0.05, ** p<0.01, *** p<0.001 and **** p<0.0001.