Table 1. Artificial APCs used in this study.
aAPC name | Cytokine transgene |
Clone 9 | None |
Clone 4 | Membrane-bound IL-15 mutein (mbIL15) |
Clone 27 | IL-15 fused to IL-15Rα with linker |
Clone 9.mbIL21 | Membrane-bound IL-21 mutein (mbIL21) |
Clone D2 | mbIL15 and mbIL21 |
All aAPCs include the transgenes for tCD19, CD64, CD86, and CD137L.