. 2012 Jan 18;7(1):e30571. doi: 10.1371/journal.pone.0030571

Table 4. Fatty acid composition of the hypothalamus (% of total fat).

Fatty Acids	CT	HF	FS 10%	OL 10%
C14:0	0.15±0.03	0.177±0.05	0.11±0.05	0.14±0.03
C16:0	22.85±1.28	22.28±0.68	24.78±1.27	23.47±0.98
C18:0	21.4±0.51	20.63±0.19	22±1.1	21.78±1.1
C20:0	0.355±0.09	0.42±0.07^# ^a	0.244±0.12^b	0.22±0.015^a
C22:0	0.23±0.04	0.24±0.01^# ^a	0.155±0.01^b	0.13±0.08^b
Σ SFA	44.9±1.9	44.33±1.1	45.6±0.26	44.56±1.8
C16:1 ω7	0.805±0.03	0.75±0.02	0.877±0.19	0.8±0.2
C18:1 ω9	24.98±1.65	25.17±0.54	24.05±3.16	23.07±2.12
Σ MUFA	26.75±0.18	30.02±0.46^# ^a	26.72±3.76^a	25.76±0.95^b
C18:2 ω6	1.9±0.71	2.56±0.1	-	-
C18:3 ω3	0.07±0.02	0.12±0.002	-	-
C20:4 ω6	10.17±0.78	9.73±0.61	10.08±2.87	11.53±2.23
C20:5 ω3	0.22±0.04	0.3±0.07^a	0.17±0.07^b	0.177±0.07^b
C22:5 ω3	0.31±0.09	0.14±0.04^# ^a	0.28±0.11^b	0.16±0.09^a
C22:6 ω3	15.67±0.72	15.33±0.24	16.27±1.02	17.7±1.4
Σ PUFA	28.36±0.92	25.6±0.54^# ^a	27.67±4.03^a ^b	29.62±0.98^b
Σ ω6	12.1±0.11	12.3±2.16	10.13±2	11.57±1.9
Σ ω3	16.3±0.7	15.9±1.11	16.74±1.14	18.04±1.15
ω6:ω3 ratio	1.0:1.34	1.0:1.29	1.0:1.65	1.0:1.55

CT, control diet; FS 10%, flax seed oil substituted 10%; HF, high fat diet; MUFA, monounsaturated fatty acid; OL 10%, olive oil substituted 10%; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid.

, mean significant difference between CT an HF groups by Student’s test (P<0.05).

^a–b

, mean values followed by the same letter in the line are not different by Tukey’s test (P< 0.05).

Σ SFA, includes 8:0, 10:0, 12:0 and 17:0.

Σ MUFA, includes 14:1, 17:1, 20:1(ω-7) and 24:1.

Σ PUFA, includes 18:3(ω-6), 20:2(ω-6), 20:3(ω-6) and 22:5(ω-6).