Table 1.
Tabulated GPCR sequence count at various stages of processing
| S. mansoni | S.mediterranea | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Family | HMM | MC | H | Final | HMM | R | MC | H | R | Final |
| G | 2 | 2 | 3 | 2 | 6 | 6 | 6 | 10 | 9 | 9 |
| R | 77 | 74 | 105 | 105 | 270 | 256 | - | 291 | 418 | 418 |
| AS | 4 | 4 | 5 | 5 | 11 | 11 | 11 | 30 | 24 | 22 |
| F | 5 | 4 | 5 | 5 | 10 | 8 | 8 | 11 | 10 | 11 |
Sequence counts are provided for each GPCR family at different stages in the receptor mining protocol. The S. mansoni count is shown after application of the TM-focused HMM and filtering of the predicted proteome (HMM), extensive manual curation (MC), homology-based searches against the nucleotide assembly (H) and a final round of manual curation (Final). This progression is similarly displayed for S. mediterranea, with additional stages for the shedding of redundant sequences using BLAT (R).