Table 3.
Biomarker Levels Stratified by Appendicitis Status
| Biomarker | No Appendicitis (n=116) | Non-Perforated Appendicitis (n = 43) | P value# | Perforated Appendicitis (n=15 ) | P value* |
|---|---|---|---|---|---|
| WBC (x 103/μL) | 10.93 (±5.7) | 15.8 (±3.8) | <0.001 | 16.8 (±4.4) | NS |
| Serum LRG (ng/ml) | 53,593 (29,897–117,492) | 84,763 (66,728–135,479) | 0.001 | 168,546 (71,497–202,579) | 0.05 |
| Urine LRG (ng/ml) | 225.2 (46.5–1,442.8) | 252.7 (106.7–2,547.5) | NS | 20,576.8 (1750.4–38,544.3) | <0.001 |
| Plasma calprotectin (ng/ml) | 221.9 (147.3–329.8) | 275.6 (238.4–378.4) | 0.01 | 490.4 (436.4–648.2) | <0.001 |
| Urine calprotectin (ng/ml) | 10.3 (5.0–46.7) | 11.0 (5.5–26.1) | NS | 36.4 (6.8–62.3) | NS |
Values are reported as mean (± SD) or median (25%–75% IQR)
#
P value of comparison of no appendicitis and those patients with non-perforated appendicitis
*
P value of comparison of non-perforated appendicitis to those patients with perforated appendicitis
LRG = leucine-rich alpha glycoprotein-1; WBC = white blood cell count; NS = not significant