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. Author manuscript; available in PMC: 2013 Jan 15.
Published in final edited form as: Clin Cancer Res. 2011 Oct 28;18(2):408–416. doi: 10.1158/1078-0432.CCR-11-0946

Figure 1. Gene set enrichment analysis.

Figure 1

Enrichment plot of gene set PEART_HISTONE_UP. The gene set that was most similar to the genes up-regulated in class 1 UMs (relative to class 2) using GSEA was PEART_HISTONE_UP, which consisted of genes up-regulated by the HDAC inhibitors SAHA and depsipeptide. Genes that are overrepresented in class 1 tumors show a peak enrichment score (ES) that is positive and to the left of the plot, and those that are overrepresented in class 2 tumors show a peak ES that is negative and to the right of the plot.