TABLE 4. Transcription factors differentially expressed in CD8αα+ Treg.
| CD8αα+ vs. CD8αβ+ |
Gene Name |
Gene Alias | Annotation | Entrez Gene ID |
|---|---|---|---|---|
| 17.7 | Rora | Nr1f1 | RAR-related orphan receptor alpha | 19883 |
| 8.4 | Pgr | NR3C3, PR | progesterone receptor | 18667 |
| 8.4 | EST | RIKEN cDNA 2610305D13 gene | 112422 | |
| 6.6 | EST | RIKEN cDNA 4930422I07 gene | 71640 | |
| 5.9 | Onecut2 | Oc2 | one cut domain, family member 2 | 225631 |
| 5.7 | Hmgn1 | Hmg14 | high mobility group nucleosomal binding domain 1 |
15312 |
| 0.12 | Zfp422 | Krox25, Krox26 |
zinc finger protein 422 | 67255 |
| 0.12 | Zfp429 | Rsl2 | zinc finger protein 429 | 72807 |
| 0.09 | Rai14 | Ankycorbin, Norpeg |
retinoic acid induced 14 | 75646 |
| 0.06 | EST | Zfp874 | zinc finger protein 874 | 238692 |
| 0.04 | Tanc2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
77097 | |
| 0.02 | Ctnnd2 | GT24, NPRAP |
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm- repeat protein) |
1501 |
| 0.12 | Basp1 | CAP23, AP22 | brain abundant, membrane attached signal protein 1 |
10409 |
| 0.12 | EST | cDNA sequence BC094916 | 545384 | |
| 0.09 | Mycn | N-myc | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) |
18109 |
Values are expressed as normalized mRNA fold expression between CD8□α+ Treg clone 2D11 and CD8αβ+ T cell clone OT-1 (CD8αα+ vs. CD8αβ+). Data are sorted based on gene expression preference in CD8αα+ Treg populations.