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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Mol Psychiatry. 2011 Jul 12;17(9):918–925. doi: 10.1038/mp.2011.86

Figure 1.

Figure 1

A) Averaged DA D2 receptor availability (D2R) images with oral methylphenidate (MPH 60 mg) and placebo between MPH and placebo (PL) of 16 METH abusers and 15 control subjects. The D2R images are scaled with respect to the maximum Vd ratio value of the control subjects with oral PL. The images are presented by using the rainbow scale, where red represents highest value and violet represents lowest value. Binding of [11C]raclopride is lowest in the METH abusers with oral MPH. B) SPM images (p < 0.005, small volume correction, multiple comparison) are superimposed on a structural MR image. The images of differences between MPH and PL for the METH abusers and control subjects as well as the Δ (MPH – placebo) image between METH abusers and control subjects are presented by using yellow-red color, where yellow represents highest value and red represents lowest value.