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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Am J Surg Pathol. 2012 Feb;36(2):235–241. doi: 10.1097/PAS.0b013e3182376e36

Table 2.

Associations between vascular invasion status and histologic characteristics of blood vessels around present vascular invasion

Histologic factors Vascular invasion P-value
Absent Present
Luminal
lymphocytes (≥5)
Absent (N=128) 50 (39%) 78 (61%) 0.10
Present (N=81) 22 (27%) 59 (73%)
Luminal
obstruction
Absent (N=122) 45 (37%) 77 (63%) 0.46
Present (N=87) 27 (31%) 60 (69%)
Intimal
lymphocytes (≥5)
Absent (N=139) 58 (42%) 81 (58%) 0.002*
Present (N=70) 14 (20%) 56 (80%)
Intimal fibrosis Absent (N=83) 38 (46%) 45 (54%) 0.007*
Present (N=126) 34 (27%) 92 (73%)
Medial
lymphocytes (≥5)
Absent (N=153) 57 (37%) 96 (63%) 0.19
Present (N=56) 15 (27%) 41 (73%)
Medial fibrosis Absent (N=122) 53 (43%) 69 (57%) 0.001*
Present (N=87) 19 (22%) 68 (78%)
Cancer cells in
vascular wall
Absent (N=132) 61 (46%) 71 (54%) <0.0001*
Present (N=77) 11 (14%) 66 (86%)
*

Significant at the level of p<0.05.