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. Author manuscript; available in PMC: 2012 Jul 15.
Published in final edited form as: Cancer Res. 2011 Nov 29;72(2):472–481. doi: 10.1158/0008-5472.CAN-11-1628

Figure 3. Effect of JNK-deficiency on mammary epithelial cell motility and invasion.

Figure 3

A,B) Primary cultures of CreERT (Control) and Jnk1Δ/Δ Jnk2−/− CreERT mammary epithelial cells prepared from tamoxifen-treated mice were examined using Boyden chambers coated with Collagen I (A) or with a Matrigel layer (B). The relative number of cells that moved from the upper chamber to the lower chamber is presented (mean ± SD; n = 5). Significant differences between Control cells and JNK-deficient cells are indicated with an asterisk (*, p < 0.05; **, p < 0.001).