TABLE 2.
Biodistribution of 99mTcO-N3S-PEG2-Probestin in HT-1080 tumor bearing nude mice at 1 hr p.i. Values are expressed as the mean ± SD; N = 4.
Tissue | %ID/g of tissue | %ID/organ |
---|---|---|
Blood | 0.60 ± 0.33 | 0.74 ± 0.41 |
Heart | 1.18 ± 0.22 | 0.12 ± 0.02 |
Lung | 0.91 ± 0.53 | 0.15 ± 0.02 |
Liver | 12.0 ± 0.8 | 12.6 ± 1.1 |
Spleen | 2.40 ± 0.45 | 0.28 ± 0.07 |
Stomach | 1.28 ± 0.59 | 0.54 ± 0.19 |
Intestine | 4.78 ± 0.33 | 10.8 ± 1.4 |
Kidney | 48.0 ± 3.4 | 15.7 ± 2.2 |
Muscle | 0.54 ± 0.25 | 4.69 ± 2.14 |
Tumor | 2.88 ± 0.64 | 3.63 ± 2.29 |
Tumor/Blood | 4.8 | - |
Tumor/Muscle | 5.3 | - |