Table 3.

Inhibition of HERG1 channel protein expression reduces cell proliferation in SCLC cells

Cell line	Control	siBlockiT	siHERG1
SW2	1.00 ± 0.06	0.97 ± 0.05	0.42 ± 0.06***
OH1	1.00 ± 0.08	0.84 ± 0.08	0.73 ± 0.07*
OH3	1.00 ± 0.09	0.49 ± 0.03***	0.21 ± 0.03***
H82	1.00 ± 0.06	0.82 ± 0.05	0.36 ± 0.03***

Cell proliferation measured in four SCLC cell lines (SW2, OH1, OH3, H82) after incubation with Lipofectamine alone (control), siBlockiT, and siRNA against ERG1 (siHERG1) for 96 h (mean ± SEM). Each mean value was calculated from 12 measurements and normalized to the mean value of the corresponding control. The level of statistical significance as compared with the controls was calculated by using the t-test with Bonferroni correction

*p < 0.05, **p < 0.01, ***p < 0.001 are the levels of significance