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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Am J Surg Pathol. 2012 Feb;36(2):173–184. doi: 10.1097/PAS.0b013e3182417d36

Figure 2. Immunohistochemical labeling patterns for DAXX and ATRX.

Figure 2

(A) Example of positive nuclear labeling for DAXX in a large cell neuroendocrine carcinoma. (B) Loss of nuclear labeling of DAXX in a well-differentiated neuroendocrine tumor. Endothelial cells and lymphocytes within the stroma are positive. (C) Positive nuclear labeling for ATRX in a small cell neuroendocrine carcinoma. (D) Loss of nuclear labeling of ATRX in a well-differentiated neuroendocrine tumor. Similar to that for DAXX shown in panel B, endothelial cells and lymphocytes within the stroma are positive (original magnifications x200).