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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Am J Surg Pathol. 2012 Feb;36(2):242–252. doi: 10.1097/PAS.0b013e31823d07f3

Figure 1.

Figure 1

Scoring of immunohistochemical staining intensity in typical examples (A: ileal neuroendocrine carcinoma, B: neuroendocrine carcinoma of the gall bladder, C: pulmonary carcinoid tumor). A: 3+ staining intensity represents strong staining at low magnification and fully circumferential staining of tumor cells membranes at high magnification (inset). B: 2+ staining intensity equals strong staining at low magnification, but no staining of the entire tumor cell circumference at high magnification (inset). C: 1+ staining intensity is defined by weak staining of the tumor cell membranes at low and high (inset) magnification.