Table 1.
Extracellular total antioxidant capacity (TAC) and total oxidative stress (TOS) levels in cultured rat hepatocytes maintained 48 h in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), eicosapentaenoic acid (EPA) and their combinations
| Treatments | TAC (mmol Trolox Equiv./L) | TOS (μmol H2O2 Equiv./L) |
|---|---|---|
| Control | 5.1 ± 0.5c | 8.3 ± 2.1a |
| TCDD 1 | 4.1 ± 0.6d | 11.4 ± 2.6c |
| TCDD 2 | 3.4 ± 0.4e | 16.4 ± 2.9e |
| EPA 1 | 5.2 ± 0.6c | 8.4 ± 3.1a |
| EPA 2 | 5.8 ± 0.5b | 8.3 ± 2.5a |
| EPA 3 | 6.3 ± 0.7a | 8.2 ± 2.4a |
| TCDD 1 + EPA 1 | 4.3 ± 0.4d | 10.8 ± 3.1c |
| TCDD 1 + EPA 2 | 4.9 ± 0.6c | 9.5 ± 2.7b |
| TCDD 1 + EPA 3 | 5.2 ± 0.5c | 8.5 ± 2.7a |
| TCDD 2 + EPA 1 | 3.8 ± 0.6e | 14.8 ± 3.4d |
| TCDD 2 + EPA 2 | 4.3 ± 0.7d | 12.6 ± 3.1cd |
| TCDD 2 + EPA 3 | 4.5 ± 0.5d | 10.3 ± 2.5c |
Abbreviations are as in Fig. 1. Means shown by the same letter are not significantly different from each other at a level of 5%, using Duncan’s test