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. 2012 Jan 28;18(4):375–382. doi: 10.3748/wjg.v18.i4.375

Table 2.

Comparison of sensitivity, specificity, positive predictive value, negative predictive value between liquid-based cytology and DNA ploidy method based on moderate dysplasia or worse as threshold

Threshold for positivity Total Se(%) Sp(%) PPV (%) NPV (%)
Cytology ASCUS+ 452 75.00  91.91 50.00 97.15
LSIL+ 452 52.27  99.02 85.19 95.06
HSIL+ 452 18.18  100.00 100.00 91.89
DNA ploidy At least 1 5cER cell 452 90.91 70.83 25.16 98.63
At least 2 5cER cell 452 86.36 84.07 36.89 98.28
At least 3 5cER cell 452 79.55 92.65 53.85 97.67
At least 4 5cER cell 452 77.27 96.81 72.34 97.53
At least 5 5cER cell 452 75.00 98.53 84.62 97.34

ASCUS: Atypical squamous cells of undetermined significance; LSIL: Low-grade squamous intraepithelial lesions; HSIL: High grade squamous intraepithelial lesion; Se: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value.