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Proposed dual role of the upregulation of members of the suppressor of cytokines family by hepatitis C virus: simultaneous impairment of the insulin and IFN-a signaling systems. HCV: Hepatitis C virus; SOC: Suppressor of cytokines; IRS-1: Insulin receptor substrate 1; STAT1: Signal transducers and activators of transcription1; IFN-α: Interferon-α.
