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. 2011 Nov;59(11):1009–1021. doi: 10.1369/0022155411423406

Figure 2.

Figure 2.

Dentin sialophosphoprotein (DSPP)–lacZ expression pattern in 1-month-old homozygous Dspp knockout mice. These mice were selected for tracking the expression pattern in various soft tissues. The wild-type C57BL/6J mice of same age were used as a control. The expression of the lacZ gene was observed in (A) submandibular salivary gland (denoted as SM) and more strongly in the sublingual (denoted as SL and pointed by white arrow) salivary gland of the Dspp null mice (right); (B) femoral head cartilage of the Dspp null mice (right) was pointed by a white arrow, whereas the diaphysis region of the long bone was indicted by an arrowhead; (C) articular cartilage (AC) and distal femoral condyle (white arrow) in the knee and growth plate region of the long bone (right); (D) articular cartilage of the mandibular condyle (denoted by white asterisk) of Dspp knockout mice; and (E) the kidneys, in which the junction of the renal cortex (marked by a white line as RC) and renal medulla (shown as RM) demonstrated strong lacZ signals. (F) Expression of lacZ gene was not observed in the heart.