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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Oct 7;1822(2):196–203. doi: 10.1016/j.bbadis.2011.09.019

Fig. 8. IL-18 increases epithelial cells paracellular permeability.

Fig. 8

YAM cells were treated with 10, 50 and 100ng/ml of recombinant IL-18 for ~16 hours. FITC-dextran 30μg/ml was added to the apical chamber. Samples were collected from the apical and basal chambers at various time points and the concentration of tracer (FITC dextran) was determined. Paracellular permeability to dextran was expressed as ratio of apical to basolateral flux. Value is means ± SEM from two different experiments and each group contains three transwells in each experiment. *p<0.05 vs. other groups.