Table 4b. Non-seminomas and normal testicular samples: (b) analysis of gene panels, based on logistic regression model, considering optimal cutoff for differentiating both groups.
| Combined genes | Cutoff based on predictive probability of tumor a | Sensitivity (%) | Specificity (%) | AUC (95% CI) |
|---|---|---|---|---|
| MLH1, APC, and ER-β | 0.225668 | 85.7 (57.2–98.2) | 82.6 (61.2–95.1) | 0.89 (0.75 – 1.00) |
Abbreviations: AUC=area under the curve; CI=confidence interval.
a
Predictive probabilities were obtained from the logistic regression models.