Table 5a. Seminomas and non-seminoma testicular samples: (a) promoter methylation frequency in seminomas and non-seminoma testicular samples.
| Non-seminoma | Seminoma | ||
|---|---|---|---|
| Genes | Cutoff | Number of tumors with methylation/total number of tumors (%, 95% CI) | Number of tumors with methylation/total number of tumors (%, 95% CI) |
| AIM1 | 44.817 | 3/14 (21.4, 4.7–50.8) | 0/43 (0, 0–8.2) |
| ARF | 0.3 | 0/14 (0, 0–6.9) | 5/43 (11.6, 3.9–25.1) |
| CCNA1 | 8.173 | 2/14 (14.3, 1.8–42.8) | 2/43 (4.6, 0.6–15.8) |
| MCAM | 1073 | 10/14 (71.4, 41.9–91.6) | 14/43 (32.6, 19.1–48.5) |
| MGMT | 0.193 | 7/14 (50, 23.0–77.0) | 1/43 (2.3, 0.1–12.3) |
| MLH1 | 0.096 | 10/14 (71.4, 41.9–91.6) | 12/43 (27.9, 15.3–43.7) |
| PGP9 | 177.09 | 2/14 (14.3, 1.8–42.8) | 4/43 (9.3, 2.6–22.1) |
| S100 | 858.15 | 8/14 (57.1, 28.9–82.3) | 0/43 (0, 0–8.2) |
| SSBP2 | 623.99 | 8/14 (57.1, 28.9–82.3) | 0/43 (0, 0–8.2) |
| APC | 19.077 | 7/14 (50, 23.0–77.0) | 5/43 (11.6, 3.9–25.1) |
| RAR-β2 | 14.273 | 3/14 (21.4, 4.7–50.8) | 1/43 (2.3, 0.1–12.3) |
| VGF | 0.023 | 7/14 (50, 23.0–77.0) | 7/43 (16.3, 6.8–30.7) |
| ER-α | 72.072 | 5/14 (35.7, 12.8–64.9) | 8/43 (18.6, 8.4–33.4) |
| ER-β | 10.145 | 9/14 (64.3, 35.1–87.2) | 12/43 (27.9, 15.3–43.7) |
| FKBP4 | 35.001 | 5/14 (35.7, 12.8–64.9) | 1/43 (2.3, 0.1–12.3) |
Abbreviation: CI=confidence interval.