Table 2.

Genotype distribution and allele frequency of 2245G/A polymorphisms in the groups studied

Clinical group	Genotype distribution			Allele frequency (%)		p Value	HWE
	GG	GA	AA	G	A
Control (n=235)	209 (88.9)	26 (11.1)	0 (0.0)	94.5	5.5	–	0.81
DNR (n=171)	143 (83.6)	28 (16.4)	0 (0.0)	91.8	8.2	NS	1.36
DR (n=171)	119 (68.6)	52 (31.4)	0 (0.0)	84.8	15.2	<0.001 (<0.01*)	5.5

Data are reported as values with per cent in parentheses unless otherwise indicated.

^*Compared with DNR.

DNR, diabetic non-retinopathy; DR, diabetic retinopathy; HWE, Hardy–Weinberg equilibrium in χ² value.