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. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: Cell Metab. 2011 Nov 17;14(6):780–790. doi: 10.1016/j.cmet.2011.10.009

Figure 5. Genes enhancing hepatic thyroid hormone metabolism are Nr1i3-resistant in HFD-fed mice.

Figure 5

Expression of various genes in the liver was measured via QPCR and normalized to Rn18S expression in C57Bl/6 mice on chow (n = 4, n = 4) or HFD (n = 4, n = 4). A, Expression of the TH sensitive genes Thrsp and Fasn. B, Expression of Nr1i3 and Cyp2b10. C, Expression of the Nr1i3-target genes: Sult1a1, Sult2a1, Sult1d1 and Ugt1a1. D, Expression of Thrβ1. In all panels, data are presented as mean ± SEM. Significance was measured with 2-way ANOVA with Bonferroni post hoc test. * = p < 0.05; ** = p < 0.01; *** = p < 0.001.

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