FIG. 9.

Effect of lateral traumatic brain injury (TBI) on spine-associated Rap guanosine triphosphatase activating protein (SPAR) immunoreactivity. The ipsilateral and contralateral hemispheres of the hippocampus and neocortex were dissected from adult rats at 18 h, 24 h, and 48 h after lateral fluid percussion TBI, separately homogenized, and subjected to immunoblotting with an antibody recognizing SPAR. No change in SPAR immunoreactivity was detected at any time point tested, in the ipsilateral hippocampus (A), contralateral hippocampus (B), ipsilateral neocortex (C), or contralateral neocortex (D), relative to controls. All comparisons were made by one-way analysis of variance with Dunnett's post-hoc test (n.s., no significant differences).