Table 3.
Medication Use
| ADHD Medication | ADHD | ADHD + RD | P Value | ||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Long-Acting Stimulants | |||||
| Adderall XR | 30901 | 31.6 | 61 | 23.0 | 0.003 |
| Concerta | 30976 | 31.7 | 86 | 32.5 | 0.794 |
| Daytrana | 2749 | 2.8 | 11 | 4.2 | 0.189 |
| Focalin XR | 8002 | 8.2 | 30 | 11.3 | 0.064 |
| Metadate CD | 5426 | 5.6 | 19 | 7.2 | 0.251 |
| Metadate ER | 193 | 0.2 | 0 | 0.0 | 1.000 |
| Methylin ER | 1083 | 1.1 | 5 | 1.9 | 0.227 |
| Methylphenidate HCL ER | 0 | 0.0 | 0 | 0.0 | N/A |
| Methylphenidate HCL SR | 0 | 0.0 | 0 | 0.0 | N/A |
| Ritalin LA | 4574 | 4.7 | 15 | 5.7 | 0.451 |
| Ritalin SR | 39 | 0.0 | 0 | 0.0 | 1.000 |
| Vyvanse | 262 | 0.3 | 0 | 0.0 | 1.000 |
| Total Long-Acting | 69623 | 71.3 | 181 | 68.3 | 0.288 |
| Short-Acting Stimulants | |||||
| Adderall | 381 | 0.4 | 1 | 0.4 | 1.000 |
| Amphetamine Salt Combo | 9289 | 9.5 | 13 | 4.9 | 0.011 |
| Amphetamine/Dextroamph | 0 | 0.0 | 0 | 0.0 | N/A |
| Cylert | 0 | 0.0 | 0 | 0.0 | N/A |
| Desoxyn | 11 | 0.0 | 0 | 0.0 | 1.000 |
| Dexedrine | 27 | 0.0 | 0 | 0.0 | 1.000 |
| Dexmethylphenidate HCL | 109 | 0.1 | 1 | 0.4 | 0.258 |
| Dextroamphetamine Sulfate | 1231 | 1.3 | 1 | 0.4 | 0.272 |
| Dextrostat | 48 | 0.0 | 1 | 0.4 | 0.124 |
| Dexampex | 0 | 0.0 | 0 | 0.0 | N/A |
| Focalin | 3098 | 3.2 | 11 | 4.2 | 0.363 |
| Methamphetamine HCL | 0 | 0.0 | 0 | 0.0 | N/A |
| Methylin | 4986 | 5.1 | 13 | 4.9 | 0.884 |
| Methylphenidate HCL | 6701 | 6.9 | 19 | 7.2 | 0.841 |
| Methylphenidate Hcl SA | 0 | 0.0 | 0 | 0.0 | N/A |
| Pemoline | 10 | 0.0 | 0 | 0.0 | 1.000 |
| Ritalin | 397 | 0.4 | 2 | 0.8 | 0.293 |
| Provigil | 234 | 0.2 | 0 | 0.0 | 1.000 |
| Total Short-Acting | 22739 | 23.3 | 54 | 20.4 | 0.265 |
| Total Stimulants | 75354 | 77.1 | 190 | 71.7 | 0.036 |
| Non-Stimulants | |||||
| Atomoxetine | 13732 | 14.1 | 34 | 12.8 | 0.567 |
| Bupropion | 3486 | 3.6 | 10 | 3.8 | 0.857 |
| Alpha 2 Agonists | 11296 | 11.6 | 32 | 12.1 | 0.794 |
| Total Non-Stimulants | 25506 | 26.1 | 65 | 24.5 | 0.559 |
| Medications used to treat Other Mental Health Conditions | ADHD | ADHD + RD | P Value | ||
| N | % | N | % | ||
| Anti-depressants | |||||
| MAOI's | 0 | 0.0 | 0 | 0.0 | N/A |
| Tricyclics | 1734 | 1.8 | 3 | 1.1 | 0.638 |
| SSRI's | 9508 | 9.7 | 26 | 9.8 | 0.965 |
| SNRI's | 772 | 0.8 | 1 | 0.4 | 0.729 |
| Other | 5105 | 5.2 | 18 | 6.8 | 0.252 |
| Total Antidepressants | 14966 | 15.3 | 43 | 16.2 | 0.682 |
| Antimanic (bipolar) agents | 7208 | 7.4 | 21 | 7.9 | 0.734 |
| Antipsychotics | |||||
| Typical | 444 | 0.5 | 0 | 0.0 | 0.638 |
| Atypical | 15593 | 16.0 | 52 | 19.6 | 0.104 |
| Total Antipsychotics | 15703 | 16.1 | 52 | 19.6 | 0.116 |
| Anxiolytics | |||||
| Benzodiazepines | 1807 | 1.8 | 3 | 1.1 | 0.643 |
| Others | 2388 | 2.4 | 5 | 1.9 | 0.557 |
| Total Anxiolytics | 3982 | 4.1 | 8 | 3.0 | 0.385 |
All comorbidties examined from index date through end of post-period.
Based upon univariate analyses with chi-square tests for variables with counts of at least 5 and Fischer's exact test if any cell had less than 5 observations.