Table 2.

IPA analysis overview

Comparison	Analysis	Top networks	Score	Top Diseases and Disorders	p-Value	# of Molecules	Top Molecular and Cellular Functions	p-Value	# of Molecules
EnD vs. EnA	Transcriptomics	Lipid Metabolism, Small Molecule Biochemistry, Vitamin and Mineral Metabolism	48	Cancer	< 0.0161	23	Lipid Metabolism	< 0.0184	6
		Lipid Metabolism, Small Molecule Biochemistry, Genetic Disorder	30	Hematological Disease	< 0.0132	12	Small Molecule Biochemistry	< 0.0184	10
		Gene Expression, Nutritional Disease, Cellular Development	22	Gastrointestinal Disease	< 0.0105	9	Vitamin and Mineral Metabolism	< 0.0175	12
	Proteomics &	Cellular Assembly and Organization, Nucleic Acid Metabolism, Small Molecule Biochemistry	25	Neurological Disease	< 0.0106	7	Cellular Growth and Proliferation	< 0.0382	7
				Genetic Disorder	< 0.0486	8	Cell Morphology	< 0.0297	4
				Cancer	< 0.0394	7	Cellular Assembly and Organization	< 0.0346	6
EnD vs. UPSC-A	Transcriptomics	Organism Injury and Abnormalities, Cardiac Necrosis/Cell Death, Cell Death*	44	Cancer	< 0.0196	31	Cellular Growth and Proliferation	< 0.0212	28
		Organ Morphology, Reproductive System Development and Function, Skeletal and Muscular Disorders #	28	Genetic Disorder	< 0.0234	47	Cell-To-Cell Signaling and Interaction	< 0.0234	11
		Cellular Development, Cellular Growth and Proliferation, Cancer	20	Reproductive System Disease	< 0.0196	12	Cell Death	< 0.0234	26
		Cardiovascular Disease, Hematological Disease, Skeletal and Muscular Disorders	19
		Endocrine System Development and Function, Small Molecule Biochemistry, Gene Expression	15
	Proteomics &	Lipid Metabolism, Small Molecule Biochemistry, Cell Morphology *, #	25	Cancer	< 0.0428	7	Amino Acid Metabolism	< 0.0150	2
				Gastrointestinal Disease	< 0.0214	4	Cell Morphology	< 0.010	1
				Inflammatory Disease	< 0.0479	2	Cellular Assembly and Organization	< 0.0125	2
EnA vs. UPSC-A	Transcriptomics	Cardiovascular System Development and Function, Cell Cycle, Lipid Metabolism	28	Cardiovascular Disease	< 0.0430	12	Gene Expression	< 0.0245	7
		Cell Death, Cellular Movement, Hematological System Development and Function	28	Development Disorder	< 0.0301	5	Cell Death	< 0.0338	15
		Cellular Assembly and Organization, Cellular Function and Maintenance, Cell Signaling	22	Connective Tissue Disorder	< 0.0487	9	Cellular Movement	< 0.0485	8

& Refers to Gemoll et al. [18]

* Overlapping of marked networks via platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) dimer (PDGFBB)

# Overlapping of marked networks via beta-Actin (ACTB)

EnD, endometrioid diploid

EnA, endometrioid aneuploid

UPSC-A, UPSC aneuploid