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. 2011 Dec 7;8:100. doi: 10.1186/1742-4690-8-100

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Copyright ©2011 Takamori et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Impaired proliferation of Tax-specific but not CMVpp65-specific CD8⁺T-cells in sATL patients. For antigen-specific T-cell proliferation, PBMCs from sATL (#110; square, #353; triangle) and cATL (#224; circle) patients were cultured for 13 days with 100 nM Tax (A) or CMV (B) peptide. Each dot indicates the percentage of tetramer⁺cells in CD8⁺T-cells at day 0 and day 13 after culture. Clinical information on ATL patients used here is as follows; sATL#110: age; 40 s, gender; F, WBC#; 11,000/μL {lymphocyte (lym); 39%, abnormal lymphocytes (ably); 4%}, cATL#224: age; 50 s, gender; F, WBC#; 7900/μL (lym; 30%, ably; 33%), sATL#353: age; 60 s, gender; M, WBC#; 4620/μL (lym; 39%, ably; 5%).