Figure 5. Surfactant effects on the constant phase parameters of AHR and corresponding morphometric assessments.

The following groups were compared: PBS (n = 10), Ova (n = 11), Surf-PBS (n = 6), and Surf-Ova (n = 12). (A) R_N and (B) G at 3 minutes were inhibited by exogenous, natural surfactant administration, (C) H at 3 minutes, (D) The larger airways are bronchoconstricted as assessed by morphometry but the surfactant effects did not reach significance (n = 4−7, *p<0.05).