Figure 6. Proliferation of U87-MG in KLF8 shRNA knockdown as well as scrambled shRNA control cells.
U87-MG cells were transfected with KLF8-shRNA or the scramble control, as indicated. Proliferation rate was high in the scrambled control cells during the whole time course after seeding. In contrast, KLF8-knockdown cells did show only minimal proliferation at day 2 after seeding but ceased further proliferation from day 3 on. Asterisk indicates significant difference (Mann-Whitney U test; p<0.05).